for the study and prevention of the unexpected perinatal death and the sudden infant death syndrome (SIDS)
The aim of this Special Issue was to collect innovative approaches that can highlight:
- which exogenous risk factors are able to alter so seriously the intrauterine environment to cause troubles in infancy;
- which diseases in the first years of life can be recognized as being of intrauterine origin as a consequence of prenatal exposure to toxics. The advantages deriving from a better understanding of the pathogenetic mechanism leading to these pathologies are certainly significant and useful for planning specific prevention strategies.
Authors were invited to submit original research articles aimed at widening the current knowledge on this field.
The articles published to date are available on the site Toxics
The contributions published in the Research Topic "New approaches to the pathogenesis of Sudden Intrauterine Unexplained Death and Sudden Infant Death Syndrome", edited by Anna M. Lavezzi and Conrad E. Johanson in collaboration with Frontiers in Neurology, now appear in a special eBook available for download on Frontiers.
The articles have been subdivided in two sections: 1) Original hypotheses; 2) Guidelines.
- Variability of the medullary arcuate nucleus in humans.
- Toxic Effect of Cigarette Smoke on Brainstem Nicotinic Receptor Expression: Primary Cause of Sudden Unexplained Perinatal Death.
- Neuropathology of early Sudden Infant Death Syndrome – Hypoplasia of the pontine Kölliker-Fuse nucleus: a possible marker of unexpected collapse during Skin-to-Skin Care.
- From fix to fit into the autoptic human brains.
- Pathobiological expression of the brain-derived neurotrophic factor (BDNF) in cerebellar cortex of sudden fetal and infant death victims.
- Detoxification genes polymorphisms in SIDS exposed to tobacco smoke.
- Mitochondrial DNA content: a new biomarker for Sudden Intruterine Unexplained Death Syndrome (SIUDS).
- EBook: “New Approaches to the Pathogenesis of Sudden Intrauterine Unexplained Death and Sudden Infant Death Syndrome”.